Research Description:
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GENETICS AND CELL BIOLOGY
- Distinguished
Honors Professor Award 2004
The Distinguished Honors Professor is nominated by students in the Honors Program
and chosen by a faculty/student committee. The Award is made possible by the
Georgia State University Foundation
- Outstanding Teaching Award for College of Arts and Science, 2002
In my lab, we are characterizing a novel ORF in C. elegans. This ORF is homologous to the human Down Syndrome Cell Adhesion Molecule (DS-CAM). We are using genetic and molecular approaches to determine the expression pattern of this gene in C. elegans development and the protein's function in cells during development. We hope that by understanding this DS-CAM gene we will learn more about how neurons develop.
Recent Publications:
Demonstrating Translation With a Student-Centered Activity, Journal of College Science Teaching, March/April 2006, Vol. 35 No. 5, p. 14-15.
Bugni JM, Poole TM, Drinkwater NR. The little mutation suppresses DEN-induced hepatocarcinogenesis in mice and abrogates genetic and hormonal modulation of susceptibility. Carcinogenesis. 2001 Nov 22 (11):1853-62.
Poole, T.M., Chiaverotti, T.A., Carabeo R.C., and Drinkwater, N.R. Genetic Analysis of Multistage Hepatocarcinogenesis. Progress in Clinical and Biological Research 395: 33-45. 1997.
Poole, T.M. and Drinkwater, N.R. Strain Dependent Effects of Sex Hormones on Hepatocarcinogenesis in Mice. (1996) Carcinogenesis 17: 191-196.
Poole, T.M. and Drinkwater, N.R. Two Genes Abrogate the Inhibition of Murine Hepatocarcinogenesis by Ovarian Hormones. (1996) The Proceedings of the National Academy of Science, USA. 93: 5848-5853.
See more publications >>
Grant Support:
Partnership for Reform in Math and Science (PRISM) Minigrant - 2005, 2006
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