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The Greer Laboratory

Publications 

  • Koues, O., Dudley, K., Truax, A., Gerhardt, D. , Bhat, K., McNeal, S. and  Greer, S.F.   Regulation of Acetylation at the MCH-II Promoter by the 19S Proteasomal ATPase Sug1. Molecular Cell Biology, July, 28 (epub ahead of print); 2008.

  • Bhat, K., Turner, J.D., Myers, S., Cape, A.C., Ting, J.T. and Greer, S.F.  The 19S Proteasome ATPase Sug1 plays a critical role in regulating MHC class II transcription.  Molecular Immunology, Apr; 45(8): 2214-24; 2008

  • Parker, C. E.; Mocanu, V.; Warren, M.R., Greer, S. F., Borchers, C.H.  Mass Spectrometric Determination of Protein Ubiquitination.  Methods in Molecular Biology (Patterson, W. C., ed.), Volume 301, Humana Press, NJ, 2005.

  • Greer, S.F., Harton, J.A., Linhoff, M.W., Janczak, C.A., Ting, J.P.-Y. and Cressman, D. Serine Residues 286, 288, and 293 within the CIITA:  A Mechanism for Down-Regulating CIITA Activity through Phosphorylation.  J. Immunol., 1:376; 2004.

  • Greer, S.F., Zika, E., Conti, B., Zhu, X.S. and Ting, J.P.-Y.  Enhancement of CIITA Transcriptional Function by Ubiquitin.  Nature Immunol., 4:1074; 2003.

  • Zika, E., Greer, S.F., Zhu, X.S., and Ting, J.P.-Y.  Association of the transcriptional coactivator CIITA with HDAC1/HDAC2 disrupts MHC-II gene expression.  Mol. Cell. Biol., 9:3091; 2003.

  • Cressman, D.E,  O’Connor, W.J., Greer, S.F., Zhu, X.S., and Ting, J.P.-Y.  Mechanisms of Nuclear Import and Export Which Control the Subcellular Localization of CIITA.  J. Immunol., 167:3626; 2002.

  • Greer, S.F., Raman, C., and Justement, L.B.  CD45 Physically Interacts with Casein Kinase 2 via a Unique Acidic Amino Acid Insert in Protein Tyrosine Phosphatase Domain II.  J. Immunol., 166:7208; 2001.

  • Greer, S.F. and Justement, L.B. The Role of CD45 in Regulation of B Lymphocyte Biology. Recent Research Developments in Immunology 1:399; 1999.

  • Greer, S.F., and Justement, L.B.  CD45 Regulates the Phosphotyrosine-Dependent Interaction Between CD22 and the SH2 Domain-Containing Protein Tyrosine Phosphatase SHP-1.  J. Immunol. 162:5278; 1999.

  • Greer, S.F., Lin, J., Clarke, C.H., and Justement, L.B.  Major Histocompatibility Class II-Mediated Signal Transduction is Regulated by the Protein Tyrosine Phosphatase CD45. J. Biol. Chem. 273:11970; 1998.